abstract：BACKGROUND:Although the role of cytokines in the development of Hashimoto's thyroiditis has already been established, its pathogenesis has not yet been clearly elucidated. The aim of our study was to investigate serum transforming growth factor-beta1 (TGF-beta1) levels in patients with Hashimoto's thyroiditis as well a...

journal_title：Archives of medical research

authors： Akinci B,Comlekci A,Yener S,Bayraktar F,Demir T,Ozcan MA,Yuksel F,Yesil S

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) is found to play important roles in acute myocardial infarction (AMI). Ventricular arrhythmias arising from AMI are leading causes of sudden cardiac death (SCD). We sought to clarify the effect of TNF-alpha early expression on ventricular arrhythmias in rats with AMI a...

journal_title：Archives of medical research

authors： Xiao H,Chen Z,Liao Y,Cheng X,Liu K,Wang Y,Wang M,Guo H

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Cardiovascular (CV) risk factors are influenced by behavioral, cultural, and social factors, suggesting that acculturation plays a significant role in the emergency and growth of chronic disease. The objective of this study was to determine the relation between CV risk factors and the main components of accu...

journal_title：Archives of medical research

authors： Rodríguez-Morán M,Guerrero-Romero F,Brito-Zurita O,Rascón-Pacheco RA,Pérez-Fuentes R,Sánchez-Guillén MC,González-Ortiz M,Martínez-Abundis E,Simental-Mendía LE,Madero A,Revilla-Monsalve C,Flores-Martínez SE,Islas-Andrade S,Cruz

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Many studies indicate that the production of reactive oxygen species (ROS) after renal ischemia/reperfusion (I/R) may initiate the cascade of cellular injury. It has been demonstrated that ozone oxidative preconditioning (OzoneOP) may prevent the damage induced by ROS and attenuate renal I/R injury. On the b...

journal_title：Archives of medical research

authors： Chen H,Xing B,Liu X,Zhan B,Zhou J,Zhu H,Chen Z

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The J wave has been seen in idiopathic ventricular fibrillation, Brugada syndrome, and early repolarization syndrome. Although these conditions share some ECG features, the clinical consequences are markedly different. J wave presentation in healthy subjects is not a rare phenomenon, although its characteris...

journal_title：Archives of medical research

authors： Kui C,Congxin H,Xi W,Yan-hong T,Okello E,Salim M,Han-hua D,Shu-ping H

更新日期：2008-02-01 00:00:00

abstract：:During the past few years, an increasing set of evidence has supported the major role of deregulation of the interaction patterns between glial cells and neurons in the pathway toward neuronal degeneration. Neurons and glial cells, together with brain vessels, constitute an integrated system for brain function. Inflam...

journal_title：Archives of medical research

authors： Rojo LE,Fernández JA,Maccioni AA,Jimenez JM,Maccioni RB

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:There is a need to assess whether human immunodeficiency virus (HIV)-infected patients are more likely than noninfected individuals to have any of the specific lipoprotein combination profiles identified as the best predictors of future cardiovascular disease in the general population. METHODS:One hundred f...

journal_title：Archives of medical research

authors： Catzin-Kuhlmann A,Castillo-Martínez L,Colín-Ramírez E,Valles V,Aguilar-Salinas CA,Sierra J,Calva JJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:A-3826G polymorphism within the promoter region of the uncoupling protein-1 (UCP-1) gene is possibly involved in the pathophysiology of obesity and metabolic disorders. However, the effects of UCP-1 A-3826G polymorphism on high-density lipoprotein cholesterol (HDL-C), a major contributor to atherosclerotic d...

journal_title：Archives of medical research

authors： Kotani K,Sakane N,Saiga K,Adachi S,Shimohiro H,Mu H,Kurozawa Y

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The apolipoprotein E-deficient mouse (ApoE) spontaneously develops hypercholesterolemia and atherosclerotic lesions in large arteries. It is also known that angiotensin II-induced hypertension accelerates the development of atherosclerosis in ApoE mice. The objective of this study was to evaluate the aortic ...

journal_title：Archives of medical research

authors： Nogueira BV,Peotta VA,Meyrelles SS,Vasquez EC

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Exercise duration of constant-load endurance tests has been recently demonstrated to be more sensitive in detecting the changes after bronchodilator administration than either walking distance or peak oxygen uptake in patients with COPD. In the present study, we questioned whether exercise duration of progre...

journal_title：Archives of medical research

authors： Metin G,Oztürk L,Duman ES,Demir T

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:It remains unclear whether the activation of kappa-opioid receptors has strong hypotensive effects under hypertensive condition, and the underlying mechanisms have not yet been investigated. Therefore, the present study is designed to use spontaneously hypertensive rats (SHR) to investigate the effects of a ...

journal_title：Archives of medical research

authors： Guo HT,Zhang RH,Huang LY,Li J,Liu YL,Bi H,Zhang QY,Wang YM,Sun X,Ma XL,Cheng L,Liu JC,Yu SQ,Yi DH,Pei JM

更新日期：2007-10-01 00:00:00

abstract：:Corneal neovascularization is a significant, sight-threatening complication of many ocular surface disorders. Various growth factors and proteinases are involved in corneal neovascularization. The data supporting a causal role for vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs) are exten...

journal_title：Archives of medical research

authors： Shakiba Y,Mostafaie A

更新日期：2007-10-01 00:00:00

abstract：:Hepatitis C represents more than 35% of liver transplant candidates worldwide. Meanwhile, hepatitis B continues to be an important cause of end-stage liver disease and hepatocellular carcinoma in Asia and Africa. Recurrent viral liver disease is a significant event after liver transplantation and continues to be one o...

journal_title：Archives of medical research

authors： Olivera-Martínez MA,Gallegos-Orozco JF

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:The human multidrug-resistant gene (MDR1) encodes P-glycoprotein (Pgp), a membrane-bound efflux transporter conferring resistance to a number of natural cytotoxic drugs and potentially toxic xenobiotics. Single-nucleotide polymorphisms (SNPs) in MDR1 gene are associated with phenotypic variation in Pgp expre...

journal_title：Archives of medical research

authors： Turgut S,Yaren A,Kursunluoglu R,Turgut G

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:We undertook this study to analyze serum and platelet gamma-glutamyltransferase (GGT) activity and total antioxidant status (TAS) concentration during the course of pneumonia and to compare them between patients with normal platelet count and those who developed reactive thrombocytosis. METHODS:Platelet cou...

journal_title：Archives of medical research

authors： Laskaj R,Dodig S,Cepelak I,Kuzman I

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Chromosomal abnormalities have important diagnostic and prognostic significance in acute lymphoblastic leukemia (ALL). The purpose of this study was to define and classify the frequency and type of chromosomal abnormalities among newly diagnosed children with ALL and compare the results with those reported f...

journal_title：Archives of medical research

authors： Udayakumar AM,Bashir WA,Pathare AV,Wali YA,Zacharia M,Khan AA,Soliman H,Al-Lamki Z,Raeburn JA

更新日期：2007-04-01 00:00:00

abstract：:Cholelithiasis is one of the most prevalent gastroenterological diseases, precipitated mainly by environmental factors. However, twin studies provided strong evidence for a role of genetic factors in the disease pathogenesis. An association between plasma lipoprotein levels and gallstone disease (GSD) was presented. A...

journal_title：Archives of medical research

authors： Kurzawski M,Juzyszyn Z,Modrzejewski A,Pawlik A,Wiatr M,Czerny B,Adamcewicz R,Droździk M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory skin disease in which several Th1 cytokines such as interleukin-1 beta (IL-beta) have been shown to play a pivotal role. Psychological stress has also been implicated in triggering or exacerbating the disease. METHODS:Salivary IL-1beta and cortisol levels of 25 patients w...

journal_title：Archives of medical research

authors： Mastrolonardo M,Alicino D,Zefferino R,Pasquini P,Picardi A

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Inflammation is a risk factor for mortality in patients with chronic renal failure (CRF). Prevention of extracellular fluid volume expansion and the use of certain drugs such as pentoxifylline (PF) may reduce inflammation and oxidative stress. The aim of this study is to analyze the effect of dietary sodium ...

journal_title：Archives of medical research

authors： Gallardo JM,de Carmen Prado-Uribe M,Amato D,Paniagua R

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Zygomycosis is an emerging mycosis of increasing relevance. Limited data exist for outcomes with contemporary therapies. METHODS:A 6-year retrospective chart review was performed in a non-oncological tertiary care center for patients with zygomycosis. RESULTS:Sixteen episodes of proven (EORTC/MSG criteria)...

journal_title：Archives of medical research

authors： Sims CR,Ostrosky-Zeichner L

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Coagulase-negative staphylococci (CoNS) have emerged as an important opportunistic pathogen isolated in hospital. Several species of CoNS have been implicated in human infections and disease especially in patients with poor health status. METHODS:A total of 71 clinical strains of CoNS were isolated from dia...

journal_title：Archives of medical research

authors： Chaieb K,Touati A,Salah AM,Hassen AB,Mahdouani K,Bakhrouf A

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Because obesity masks the need for screening, there is no previous description of dyslipidemia in healthy normal-weight children. The aims of this study were a) to determine the prevalence of disorders in lipid profile among non-obese prepubertal children, and b) to establish its association with the family ...

journal_title：Archives of medical research

authors： Guerrero-Romero F,Rodríguez-Morán M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The present study was designed to examine whether resveratrol, a potent antioxidant, protects against renal ischemia-reperfusion (I/R) injury. METHODS:Wistar albino rats were unilaterally nephrectomized and subjected to 45 min of renal pedicle occlusion followed by 6 h of reperfusion. Resveratrol (RVT, 30 m...

journal_title：Archives of medical research

authors： Sener G,Tuğtepe H,Yüksel M,Cetinel S,Gedik N,Yeğen BC

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Associations between hyperuricemia, metabolic syndrome, cardiovascular disease and diabetes have been reported. Limited information, however, is available concerning the prevalence and correlates of hyperuricemia among Thai men and women. We sought to estimate the prevalence of hyperuricemia among a populati...

journal_title：Archives of medical research

authors： Lohsoonthorn V,Dhanamun B,Williams MA

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Cellular events in cisplatin-mediated nephrotoxicity include apoptosis induction, decreased protein synthesis, changes in the subcellular redistribution of Bax mitochondrial dysfunction, DNA injury, increased lipid peroxidation, depletion of glutathione and decrease in enzymatic activity of renal antioxidant...

journal_title：Archives of medical research

authors： Borrego A,Zamora ZB,González R,Romay C,Menéndez S,Hernández F,Berlanga J,Montero T

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia is a risk factor for atherosclerotic events. Differences in lipid levels may exist in different races. Han is the largest group and Zhuang is the largest minority among the 56 nationalities in China. Geographically and linguistically, Zhuang can be classified into 43 ethnic subgroups, among wh...

journal_title：Archives of medical research

authors： Yin R,Chen Y,Pan S,He F,Liu T,Yang D,Wu J,Yao L,Lin W,Li R,Huang J

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The function of the calcium-sensing receptor (CaSR) is to maintain serum calcium concentration within a narrow physiological range. Two types of mutations have been described: activating that causes hypocalcemia and inactivating, which leads to hypercalcemia. The objective was to assess the effect of CaSR ge...

journal_title：Archives of medical research

authors： Pérez-Castrillón JL,Sanz A,Silva J,Justo I,Velasco E,Dueñas A

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:We undertook this study to compare the effectiveness and safety of antenatal daily and weekly supplementation with iron, folic acid, and vitamin B(12) in healthy, pregnant women who were not anemic at gestational week 20. METHODS:Women with singleton pregnancies and blood hemoglobin (Hb) >115 g/L at gestati...

journal_title：Archives of medical research

authors： Casanueva E,Viteri FE,Mares-Galindo M,Meza-Camacho C,Loría A,Schnaas L,Valdés-Ramos R

更新日期：2006-07-01 00:00:00

abstract：:During the process of energy production in aerobic respiration, vascular cells produce reactive oxygen species (ROS). A growing body of evidence indicates that oxidative stress refers to a condition in which cells are subjected to excessive levels of ROS. Overall vascular function is dependent upon a fine balance of o...

journal_title：Archives of medical research

authors： Rojas A,Figueroa H,Re L,Morales MA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Wind instrument playing requires a strenuous respiratory activity. Previous studies investigating effect of wind instrument playing on pulmonary function are equivocal. METHODS:In the present study, 34 male, non-smoker wind players in a military band were compared with 44 healthy non-smoker males by pulmona...

journal_title：Archives of medical research

authors： Deniz O,Savci S,Tozkoparan E,Ince DI,Ucar M,Ciftci F

更新日期：2006-05-01 00:00:00

abstract：:Heroin abuse causes various medical and surgical complications. We report a case of heroin-induced severe bilateral compartment syndrome complicated by rhabdomyolysis, acute renal failure and extremely elevated creatinine kinase. A 30-year-old male heroin addict presented to the emergency department of Mount Vernon Ho...

journal_title：Archives of medical research

authors： Abdullah MS,Al-Waili NS,Butler G,Baban NK

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Although Leishmania virulence may be modulated by environmental and genetic factors of their mammalian hosts and sand fly vectors, molecular determinants of Leishmania sp. are the key elements. This work evidences that Leishmania amazonensis axenic amastigotes produce comparatively more NO than infective pro...

journal_title：Archives of medical research

authors： Genestra M,Guedes-Silva D,Souza WJ,Cysne-Finkelstein L,Soares-Bezerra RJ,Monteiro FP,Leon LL

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum has a worldwide occurrence and its primary mode of transmission is via direct human contact including sexual means. The aim of the study was to implement a polymerase chain reaction-based assay for detection and subtyping of Molluscum contagiosum virus (MCV) in skin lesions diagnosed wi...

journal_title：Archives of medical research

authors： Saral Y,Kalkan A,Ozdarendeli A,Bulut Y,Doymaz MZ

更新日期：2006-04-01 00:00:00

abstract：:Classical descriptions of the pathology of amebiasis portray the parasite as the cause of tissue damage and destruction, and in recent years a number of amebic molecules have been identified as virulence factors. In this review we describe a series of experiments that suggest a more complex host-parasite relation, at ...

journal_title：Archives of medical research

authors： Pérez-Tamayo R,Montfort I,García AO,Ramos E,Ostria CB

更新日期：2006-02-01 00:00:00

abstract：:Hué, a city of about 300,000 inhabitants in Central Vietnam, is known as a "hot spot" for diseases caused by Entamoeba histolytica and in particular for amebic liver abscess (ALA), thus representing an excellent site for studies on the epidemiology and treatment of E. histolytica infections. Accordingly, during the la...

journal_title：Archives of medical research

authors： Blessmann J,Le Van A,Tannich E

更新日期：2006-02-01 00:00:00

abstract：:Glutamate neurotransmitter action on postsynaptic receptors is terminated by its clearance from the synaptic cleft by transporter proteins located in neurons and glial cells. Failure of glutamate removal can lead to neuronal death due to its well-known neurotoxic properties. Glutamate transporters are dependent on ext...

journal_title：Archives of medical research

authors： Camacho A,Massieu L

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The relationship between endocrine regulation and immune system has recently become the subject of intense investigations. The aim of this study was the comparative assessment of serum levels of selected hormones and insulin-like growth factor-I (IGF-I) in patients with multiple myeloma (MM) during applied t...

journal_title：Archives of medical research

authors： Hrycek A,Gruszka A

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Recently, the Expert Committee of the American Diabetes Association proposed to decrease the lower limit for normal fasting plasma glucose (FPG) levels to 5.6 mmol/L. In this regard, the aim of this study was to determine the effect of lowering the criterion for normal FPG on the identification of subjects w...

journal_title：Archives of medical research

authors： Guerrero-Romero F,Rodríguez-Morán M

更新日期：2006-01-01 00:00:00

abstract：:Global warming has serious implications for all aspects of human life, including infectious diseases. The effect of global warming depends on the complex interaction between the human host population and the causative infectious agent. From the human standpoint, changes in the environment may trigger human migration, ...

journal_title：Archives of medical research

authors： Khasnis AA,Nettleman MD

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:One of the most frequent malignancies in women worldwide is carcinoma of the uterine cervix. High-risk human papillomavirus (HPV) infection is considered the most important etiological factor of uterine cervical cancer. Our aim was to identify novel cellular genes that could potentially act as predictive mol...

journal_title：Archives of medical research

authors： Vázquez-Ortíz G,Ciudad CJ,Piña P,Vazquez K,Hidalgo A,Alatorre B,Garcia JA,Salamanca F,Peralta-Rodriguez R,Rangel A,Salcedo M

更新日期：2005-09-01 00:00:00